Welcome to the Elfenbein Lab!

Salmonella enterica is a leading cause of bacterial food-borne disease that affects more than 1 million people in the United States and more than 90 million people world-wide each year. Infection causes febrile diarrheal disease in most people. In addition to diarrheal disease, Salmonella causes the most deaths of any food-borne pathogen in the US and is a leading cause of death of children and immunosuppressed people worldwide. As a food-borne pathogen, contaminated food and water are the major cause of disease outbreaks in people. In addition to its impact on human health, Salmonella also causes diarrhea and sepsis in mammals, leading to significant impact on animal welfare. Therefore, it is imperative to understand how Salmonella thrives in infected hosts and in the environment to eradicate this zoonotic pathogen.

Recent Events in the Elfenbein Lab

  • USDA-EWD fellowship

    Congratulations to Dr. Sarah Raabis for being awarded an Early Workforce Development postdoctoral fellowship from the USDA. We are looking forward to a super cool project on pulmonary immunity, of all things! You can read …

  • Moving forward, full speed ahead!

    We are so pleased to have successfully navigated the past year through the racial unrest that is tarnishing our nation and the ongoing COVID-19 pandemic. Within the last year, we welcomed two new post-doctoral associates, …

  • New regulator of flagella-mediated motility

    Work by Dr. Trina Westerman identified a new layer contributing to the complex regulation of flagella production in Salmonella. Flagella mediate swimming motility and are essential for Salmonella to cause gastrointestinal disease. Her manuscript is …

  • Human neutrophil response to Salmonella

    Dr. Trina Westerman’s genetic screen of Salmonella mutants identifies a sulfate import mutant that reduces human neutrophil respiratory burst. Heterogeneity in Salmonella gene expression impacts the magnitude of the neutrophil antimicrobial response ex vivo, suggesting …

  • Congratulations Eddy!

    We are proud to announce that DVM/PhD student Eddy Cruz was named a 2020 Vet Fellow by the FFAR and AAVMC! Eddy will study the role of sulfur metabolites on Salmonella survival in host-relevant and …

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